Parry and Buenz argue that « self experimentation was an important part of the scientific process, allowing medical advances that would have been hard to achieve otherwise because no sane human would agree to be a research participant and no ethical review board in its right mind would approve the experiment. » [1]. This is certainly true for many cases, but there have been exceptions, and the individuals involved were likely rather sane: Almost 20 years before Forssmann, Fritz Bleichrder in Berlin performed catheterization studies on his colleague Ernst Unger and also on one of his laboratory technicians [10]. What was perhaps more important is that into the 1960s discovery was often prevented by leading clinicians who preferred dogma to knowledge.

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